Here are some frequently asked questions about the Talking Therapies Research Resource.
If the information you are looking for is not on this page, please contact our research team here.
The National Institute of Health Research (NIHR) BioResource is a large biorepository of >100,000 people with and without health problems who are willing to be approached to participate in research studies investigating the link between genes, the environment, health and disease. It is based at centres around England and is funded by the NIHR.
The NIHR Mental Health BioResource is a branch of the NIHR BioResource which aims to increase participation of people with mental health disorders in medical and psychological research. By joining the GLAD study, you will also become a part of the NIHR Mental Health BioResource and will have the opportunity to contribute to future research.
Anyone interested in taking part in the TTRR must read the participant information sheet before consenting to join the study. A short version of the information sheet can be found in click-through format on the ‘About TTRR’ page. Please find a downloadable pdf version of the full information sheet here: Information Sheet
The TTRR is only looking to recruit individuals who have been accepted onto a course of psychological therapy through IAPT. If you are interested in taking part in research, we will be launching a new study which will be open for non-IAPT service users to participate in.
To help us understand how genes influence response to psychological treatments, we will isolate and analyse your DNA from the saliva sample that you provide us. Using advanced laboratory techniques, we will then identify the sequence of your genetic code from your DNA. Your survey data will be used to gain a better understanding of your background and your response to treatment which we will link to your genetic data in order to allow us to better understand what genetic risk factors can impact response to psychological treatment. In addition, your survey data will help us to identify future studies that you will be eligible to take part in. All data that you provide us will be stored securely and be kept strictly confidential in accordance with the General Data Protection Regulation.
Keeping your information secure is our highest priority. There are a number of regulations and policies that the Talking Therapies Research Resource complies with to ensure data is protected and that biological samples are stored correctly.
Storage and work on personal data or biological data will always be in accordance with the current ethical guidelines, and the conditions of the consent you have provided. In the event that ethical guidelines are modified, the project will be further evaluated for ethical approval. All data will be stored at King’s College London and partner sites in accordance with the GDPR. Data will not be passed on to any third parties including your doctor, your insurance company or your employer.
All data will be used in an anonymised linked format with personal information being accessible only by the lead investigators and project co-ordinator. Identifiable volunteer information will only be available to the recruitment team as well as clinical staff who have DBS clearance and are bound to confidentiality by their University/NHS contract. Each member of the recruitment team and collaborating clinical staff will complete mandatory training as set out by King’s College London and the NHS to ensure policies and procedures for managing confidential data are upheld. These staff members are aware that any breach of such procedures could result in disciplinary action and or dismissal from the team/service. Personal data will be stored on a secure database and securely located within the King’s College London firewall in compliance with KCL data security policy.
Staff at the NIHR BioResource sample biorepository will ensure that genetic samples are processed in accordance with strict health and safety guidelines and under the requirements of the Human Tissue Act (HTA) 2004. The NIHR BioResource sample biorepository holds an HTA license (License number: 12624). The link between the participant ID and de-identified data will be kept in a secure database accessible only to the lead investigators and senior researchers.
If you would like to read more on how we keep your data secure, click here to go to Terms & Conditions.
Useful links for more information about use of personal and biological data:
The EU General Data Protection Regulation (GDPR)
The General Data Protection Regulation is an EU Regulation which was put in place to ensure the protection of all EU citizens’ data privacy. It also gives people the rights to access any information held about them.
King’s College London Data Protection Policy http://www.kcl.ac.uk/governancezone/GovernanceLegal/Data-Protection-Policy.aspx
This policy outlines King’s College London’s policy for protecting personal information in compliance with the General Data Protection Regulation 2018 (GDPR). The University has procedures aiming to ensure that all staff, students, and agents of the University who have access to personal data are aware of their duties and responsibilities under the GDPR.
Human Tissue Act 2004
If you provide the Talking Therapies Research Resource with a saliva sample, your biological sample is protected by the Human Tissue Act 2004. The Act regulates the removal, storage and use of human tissue and ensures all samples are collected appropriately.
Combining information from your medical records, questionnaire data, and DNA provides a comprehensive overview for researchers to use in a wide range of investigations. We will only access relevant sections of your medical records that will be helpful to our research. For example, we will request information on the details of your history with anxiety and/or depression and how well you responded to treatment. All information obtained from your medical records will be given a pseudonymised (coded) ID and kept strictly confidential and will be stored separately from your personal information (e.g. name, date of birth).
Your genome is your complete set of DNA. Our laboratory team may sequence all or part of your genetic code in order to allow us to improve our understanding of the development and treatment of a range of psychiatric conditions. Your genomic data will be stored securely using a unique ID number, and will be stored separately from any personal identifiers (e.g. name, date of birth).
You will not routinely be given access to your genetic data as we are not collecting your data for clinical diagnosis, but for more general research purposes.
We are only using the genetic data that we extract from your saliva for general research purposes, to improve healthcare and not for individual clinical diagnoses. In the rare instance that we do find something of clinical importance, we will write to your GP recommending further investigation.
Many of the additional research studies you will be invited to take part in will be looking at depression and/or anxiety with the goal of better understanding these disorders; however, you may also be contacted to take part in other types of research studies. These could be related to other mental or physical health studies indicated from either your questionnaire responses, physical characteristics, or genetic make-up. These studies may be advertised on the website here, or you may be contacted directly to ask whether you might be interested in participating. You are under no obligation to take part in additional studies. You may be invited to take part in up to four additional studies per year.
You do not normally have to disclose your research participation to your life insurer including any genetic tests that you have completed during your participation.
There are several steps involved in collaboration with the TTRR, depending on whether you are requesting access to data, samples, or would like to recruit TTRR members for your study. All requests need to be approved by the TTRR steering committee.
If you are interested in collaborating, please get in touch with the study team at ttrrAdmin@kcl.ac.uk.
We look forward to hearing from you!
To begin signing up you just need to provide your name, email address and a password. You will be sent a notification email to check we have the best way of contacting you.
After this, the TTRR enrolment process consists of four steps: